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OpenIGTLink

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The goal of OpenIGTLink is to provide a standardized mechanism to connect software/hardware through the network for image-guided therapy (IGT) applications. The features of OpenIGTLink include:

DeVIDE

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DeVIDE, or the Delft Visualisation and Image processing Development Environment, is a cross-platform software framework for the rapid prototyping, testing and deployment of visualisation and image processing algorithms. The software was developed within the Visualisation group. DeVIDE's primary (and currently only) front-end is a data-flow boxes-and-lines network editor. In this regard, it is very similar to AVS, OpenDX, Khoros or VISSION. DeVIDE integrates functionality from libraries such as VTK, ITK, GDCM, DCMTK, numpy and matplotlib. It is being very actively developed.

Bioconductor

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Bioconductor is an open source, open development software project to provide tools for the analysis and comprehension of high-throughput genomic data. It is based primarily on the R programming language.

The Bioconductor release version is updated twice each year, and is appropriate for most users. There is also a development version, to which new features and packages are added prior to incorporation in the release. A large number of meta-data packages provide pathway, organism, microarray and other annotations.

CyberUnits

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CyberUnits is a cross-platform class library for rapid programming of high-performance computer simulations in life sciences. It supports modelling for biomedical cybernetics and systems biology with Object Pascal, S and Matlab.

PUMA repository

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The PUMA Repository (Pascal units for medical applications) is a collection of reusable source code for bioinformatics. It is compatible with Lazarus and Free Pascal, parts of the source code can also be used with Delphi and winsoft Pocket Studio.
Components of the PUMA repository include a unit converter for transforming instrumentation readouts consisting of a numerical value and a measurement unit, and an HL7 engine for reading, parsing, compiling and writing HL7 messages.

SimThyr

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SimThyr is a simulation program for thyroid homeostasis. It is based on a published nonlinear parametric isomorphic model of thyrotropic feedback control. Applications of SimThyr cover generation of hypotheses for biomedical research, education and presentation. Binaries and sourcecode are available for Mac OS, Mac OS X, Windows, Linux and other Unix derivatives.

SPINA Thyr

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SPINA (structure parameter inference approach) is a method for calculating constant structure parameters of endocrine feedback control systems in vivo from hormone levels obtained from serum or plasma.

A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).

District Health Information Software 2 (DHIS 2)

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The DHIS 2 is a tool for collection, validation, analysis, and presentation of aggregate statistical data, tailored (but not limited) to integrated health information management activities. It is a generic tool rather than a pre-configured database application, with an open meta-data model and a flexible user interface that allows the user to design the contents of a specific information system without the need for programming. DHIS 2 and upwards is a modular web-based software package built with free and open source Java frameworks.

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