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OPAL

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OPAL Is a full stack web framework for building health care applications.

OPAL encourages rapid development, and elegant, pragmatic design.

Focussed on health care, it builds on years of research and design to
help you in building your app. It's free and open source.

EtherCIS

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EtherCIS (Ethereal Clinical Information System) is an Open Source platform compatible with the openEHR standard. It is design to allow simple interactions with clients using RESTful API and persist clinical data in a separate DB engine. Clinical data are exchanged using different formats:

FLAT JSON: which is a flatten representation of access path along with the corresponding field value
Canonical XML: representing an openEHR composition in standard XML
For more details on data representation in openEHR see this page