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ART-DECOR

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ART-DECOR is an open-source tool suite that supports the creation and maintenance of HL7 Templates, Value Sets as well as Data Sets and features cloud-based federated Building Block Repositories (BBR) for Templates and Value Sets. The tool offers a Data Set and a Scenario editor, two Template editors, a Value Set editor and includes browsers for various international terminologies such as LOINC.

i2b2

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i2b2 (Informatics for Integrating Biology and the Bedside) is an NIH-funded National Center for Biomedical Computing based at Partners HealthCare System. The i2b2 Center is developing a scalable informatics framework that will enable clinical researchers to use existing clinical data for discovery research and, when combined with IRB-approved genomic data, facilitate the design of targeted therapies for individual patients with diseases having genetic origins. This platform currently enjoys wide international adoption by the CTSA network, academic health centers, and industry.

NutWin

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NutWin aims to help the nutritionist in performing calculations for Nutritional Assessment, quantify nutrient intake and preparing food plans. The software, developed at Escola Paulista de Medicina from the Federal University of Sao Paulo (Unifesp) is available in Portuguese.

IDRT - Integrated Data Repository Toolkit

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i2b2 has turned out to be a very valuable component for secondary use of routine clinical data. Its pragmatic database schema allows merging of data from heterogeneous data sources, and the intuitive user interface enables easy querying and powerful processing. However, it's a component rather than a complete solution: The user is facing several barriers when integrating i2b2 into the operational workflow.

Ogles2

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Ogles2 is an interactive slice and volume visualization and analysis tool based on Open Inventor / Coin3D. Ogles2 allows for reproducing the workflow of frame based stereotactic neurosurgery. In the long run it strives for being an open source stereotactic planning and analysis system. Ogles2 is NOT APPROVED FOR CLINICAL USE.

Usagi

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Usagi is a software tool created by the Observational Health Data Sciences and Informatics (OHDSI) team and is used to help in the process of mapping codes from a source system into the standard terminologies stored in the Observational Medical Outcomes Partnership (OMOP) Vocabulary (http://www.ohdsi.org/data-standardization/vocabulary-resources/).

ACHILLES

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ACHILLES is a platform which enables the characterization, quality assessment and visualization of observational health databases. ACHILLES provides users with an interactive, exploratory framework to assess patient demographics, the prevalence of conditions, drugs and procedures, and to evaluate the distribution of values for clinical observations.

ACHILLES is intended to be implemented by organizations that have patient-level observational health databases available in their local environment.

Bioconductor

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Bioconductor is an open source, open development software project to provide tools for the analysis and comprehension of high-throughput genomic data. It is based primarily on the R programming language.

The Bioconductor release version is updated twice each year, and is appropriate for most users. There is also a development version, to which new features and packages are added prior to incorporation in the release. A large number of meta-data packages provide pathway, organism, microarray and other annotations.

DeVIDE

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DeVIDE, or the Delft Visualisation and Image processing Development Environment, is a cross-platform software framework for the rapid prototyping, testing and deployment of visualisation and image processing algorithms. The software was developed within the Visualisation group. DeVIDE's primary (and currently only) front-end is a data-flow boxes-and-lines network editor. In this regard, it is very similar to AVS, OpenDX, Khoros or VISSION. DeVIDE integrates functionality from libraries such as VTK, ITK, GDCM, DCMTK, numpy and matplotlib. It is being very actively developed.

SPINA Thyr

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SPINA (structure parameter inference approach) is a method for calculating constant structure parameters of endocrine feedback control systems in vivo from hormone levels obtained from serum or plasma.

A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).

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