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RANDI2

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RANDI2 is an open source web application for randomization within clinical trials. It supports a variety of randomization algorithms and offers a very useful set of functions for randomization data & progress visualization and trial management - for more information please visit http://www.randi2.org

SPINA Thyr

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SPINA (structure parameter inference approach) is a method for calculating constant structure parameters of endocrine feedback control systems in vivo from hormone levels obtained from serum or plasma.

A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).