SPINA (structure parameter inference approach) is a method for calculating constant structure parameters of endocrine feedback control systems in vivo from hormone levels obtained from serum or plasma.
A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).
- Read more about SPINA Thyr
- Log in to post comments
- 2360 reads