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PROSIT Disease Modelling Community

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PROSIT is an international scientific open source development community for health economic disease models in medicine. prosit [latin] = "it shall be useful"

Aim of this development community is to provide valid and lasting open source disease models for chronic diseases such as diabetes. Disease models for relevant late complications of diabetes mellitus (i.e. nephropathy, retinopathy, diabetic foot syndrome, stroke, myocardial infarction) have been developed. The future mission is to integrate also models for other chronic diseases such as asthma, COPD and more.

SimThyr

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SimThyr is a simulation program for thyroid homeostasis. It is based on a published nonlinear parametric isomorphic model of thyrotropic feedback control. Applications of SimThyr cover generation of hypotheses for biomedical research, education and presentation. Binaries and sourcecode are available for Mac OS, Mac OS X, Windows, Linux and other Unix derivatives.

CyberUnits

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CyberUnits is a cross-platform class library for rapid programming of high-performance computer simulations in life sciences. It supports modelling for biomedical cybernetics and systems biology with Object Pascal, S and Matlab.

i2b2

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i2b2 (Informatics for Integrating Biology and the Bedside) is an NIH-funded National Center for Biomedical Computing based at Partners HealthCare System. The i2b2 Center is developing a scalable informatics framework that will enable clinical researchers to use existing clinical data for discovery research and, when combined with IRB-approved genomic data, facilitate the design of targeted therapies for individual patients with diseases having genetic origins. This platform currently enjoys wide international adoption by the CTSA network, academic health centers, and industry.