ITK-SNAP is a software application used to segment structures in 3D medical images. It is the product of a decade-long collaboration between Paul Yushkevich, Ph.D., of the Penn Image Computing and Science Laboratory (PICSL)
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The Visualization Toolkit (VTK) is an open-source, freely available software system for 3D computer graphics, image processing, and visualization. It consists of a C++ class library and several interpreted interface layers including Tcl/Tk, Java, and Python. VTK supports a wide variety of visualization algorithms including scalar, vector, tensor, texture, and volumetric methods, as well as advanced modeling techniques such as implicit modeling, polygon reduction, mesh smoothing, cutting, contouring, and Delaunay triangulation.