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Laika analyzes and reports on the interoperability capabilities of EHR systems. This includes the testing for certification of EHR software products and networks.

To support EHR data interoperability testing, Laika is designed to verify the input and output of EHR data against the standards and criteria identified by the Certification Commission for Health Information Technology (CCHIT). Laika is used by the Certification Commission to perform part of the interoperability certification inspection of EHRs.

The 'epicalc' R Package

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Functions making R easy for epidemiological calculation.

Datasets from Dbase (.dbf), Stata (.dta), SPSS(.sav), EpiInfo(.rec) and Comma separated value (.csv) formats as well as R data frames can be processed to do make several epidemiological calculations.

Axial 360

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  • Axial 360 is an interface engine and connector library that enables health care systems of all types - hospital systems, lab systems, EHRs, HIEs, etc - to share clinical data when it is needed.
  • Axial 360 is built using best-of-bread open source components that enable improved scalability, extensibility, and modularity relative to other interface engines.
  • Axial 360 will feature a library of free “connectors” developed by the open source community, that will reduce the time required to interface with applications.

Grassroots DICOM (GDCM)

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Grassroots DICOM (GDCM) is an implementation of the DICOM standard designed to be open source so that researchers may access clinical data directly. GDCM includes a file format definition and a network communications protocol, both of which should be extended to provide a full set of tools for a researcher or small medical imaging vendor to interface with an existing medical database.

The 'epiR' R Package

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A package for analysing epidemiological data. Contains functions for directly and indirectly adjusting measures of disease frequency, quantifying measures of association on the basis of single or multiple strata of count data presented in a contingency table, and computing confidence intervals around incidence risk and incidence rate estimates. Miscellaneous functions for use in meta-analysis, diagnostic test interpretation, and sample size calculations.


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The main goal of the Computer Assisted Search for Epidemics (CASE) project is to develop a reliable system that generates warnings when the number of reported cases of a particular infectious disease reaches a level that indicates an unusual or unexpected rate. The system is currently in use at the Swedish Institute for Infectious Disease Control (SMI). It performs daily surveillance using data obtained from the database to which all notifiable diseases are reported in Sweden.


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Niftilib is a set of i/o libraries for reading and writing files in the nifti-1 data format. nifti-1 is a binary file format for storing medical image data, e.g. magnetic resonance image (MRI) and functional MRI (fMRI) brain images.

Niftilib currently has C, Java, MATLAB, and Python libraries; we plan to add some MATLAB/mex interfaces to the C library in the not too distant future.

DataViewer3D (DV3D)

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DataViewer3D (DV3D) is a multi-modal imaging data visualization tool offering a cross-platform, open-source solution to simultaneous data overlay visualization requirements of imaging studies.


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Gwyddion is a modular program for SPM (scanning probe microscopy) data visualization and analysis. Primarily it is intended for analysis of height fields obtained by scanning probe microscopy techniques (AFM, MFM, STM, SNOM/NSOM), however it can be generally used for any other height field and image analysis, for instance for analysis of profilometry data.

It aims to provide multiplatform modular program for 2D data analysis that could be easily extended by modules and plug-ins.