Caisis is an open source, web-based cancer data management system that integrates research with patient care. The system is freely distributed to promote scientific collaboration, and over the course of the last five years many other institutions have adopted the system. Collaboration with multiple centers has allowed Caisis to develop and evolve in an environment of constant feedback and scrutiny. This environment has shaped the features, usability, and accessibility of Caisis.
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i2b2 (Informatics for Integrating Biology and the Bedside) is an NIH-funded National Center for Biomedical Computing based at Partners HealthCare System. The i2b2 Center is developing a scalable informatics framework that will enable clinical researchers to use existing clinical data for discovery research and, when combined with IRB-approved genomic data, facilitate the design of targeted therapies for individual patients with diseases having genetic origins. This platform currently enjoys wide international adoption by the CTSA network, academic health centers, and industry.
OpenClinica is a free, open source clinical trial software platform for Electronic Data Capture (EDC) clinical data management in clinical research. The software is web-based and designed to support all types of clinical studies in diverse research settings. From the ground up, OpenClinica is built on leading, independent standards to achieve high levels of interoperability and regulatory compliance. Its modular architecture and transparent, collaborative development model offer outstanding flexibility while supporting a robust, enterprise class, regulatory compliant, solution.