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Niftilib

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Niftilib is a set of i/o libraries for reading and writing files in the nifti-1 data format. nifti-1 is a binary file format for storing medical image data, e.g. magnetic resonance image (MRI) and functional MRI (fMRI) brain images.

Niftilib currently has C, Java, MATLAB, and Python libraries; we plan to add some MATLAB/mex interfaces to the C library in the not too distant future.

ImageJ

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ImageJ is a public domain Java image processing program inspired by NIH Image for the Macintosh. It runs, either as an online applet or as a downloadable application, on any computer with a Java 1.4 or later virtual machine. Downloadable distributions are available for Windows, Mac OS, Mac OS X and Linux.

IHE open source

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This project holds an implementation of the Cross-Enterprise Document Sharing (XDS) profile as defined by IHE (ihe.net). It includes implementations of both the Document Registry and Document Repository actors.

The project is deployed at the XDS Public Registry Test Facility of the National Institute of Standards and Technology (NIST).

SPARK

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Spark is a public domain FHIR server developed in C#, initially built by Firely and as of recently being maintained by Kufu.
Spark implements a major part of the FHIR specification and has been used and tested during several HL7 WGM Connectathons.