i2b2 has turned out to be a very valuable component for secondary use of routine clinical data. Its pragmatic database schema allows merging of data from heterogeneous data sources, and the intuitive user interface enables easy querying and powerful processing. However, it's a component rather than a complete solution: The user is facing several barriers when integrating i2b2 into the operational workflow.
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The CYTOMINE project (started in 2010) is continuously developing a rich internet application using modern web technologies, databases, and machine learning to foster active and distributed collaboration and ease large-scale image exploitation. Our software is e.g. being used by life scientists to help them better evaluate drug treatments or understand biological processes directly from whole-slide tissue images, by pathologists to share and ease their diagnosis, and by teachers and students for pathology training purposes.
Open DICOM Viewer is a small display of medical images. Aimed at displaying images in a web page or patient CD. Developed in Java 1.6.
A major diffculty in image guided therapy (IGT) is acquiring the patient's anatomy intraoperatively, which can be used for registering preoperative information. Intraoperative use of standard modalities has several limitations, such as low image quality (ultrasound), radiation exposure (computed tomography) or high costs (magnetic resonance imaging). An alternative approach is using a tracked pointer and registering the acquired points to surfaces identified in preoperative images.
ITK-SNAP is a software application used to segment structures in 3D medical images. It is the product of a decade-long collaboration between Paul Yushkevich, Ph.D., of the Penn Image Computing and Science Laboratory (PICSL)
VTKEdge is no longer under active development, as its functionality has been incorporated into the Visualization Toolkit (VTK). The VTKEdge project created a library of advanced visualization and data processing techniques that complemented VTK. The custom modules to enable the use of these techniques within ParaView have also been incorporated into VTK.
ParaView is an open-source, multi-platform data analysis and visualization application. ParaView users can quickly build visualizations to analyze their data using qualitative and quantitative techniques. The data exploration can be done interactively in 3D or programmatically using ParaView's batch processing capabilities.
ParaView was developed to analyze extremely large datasets using distributed memory computing resources. It can be run on supercomputers to analyze datasets of terascale as well as on laptops for smaller data.
The Visualization Toolkit (VTK) is an open-source, freely available software system for 3D computer graphics, image processing, and visualization. It consists of a C++ class library and several interpreted interface layers including Tcl/Tk, Java, and Python. VTK supports a wide variety of visualization algorithms including scalar, vector, tensor, texture, and volumetric methods, as well as advanced modeling techniques such as implicit modeling, polygon reduction, mesh smoothing, cutting, contouring, and Delaunay triangulation.
3D Slicer is an open source software platform for medical image informatics, image processing, and three-dimensional visualization. Built over two decades through support from the National Institutes of Health and a worldwide developer community, Slicer brings free, powerful cross-platform processing tools to physicians, researchers, and the general public.
The OpenEEG project is about creating a low cost EEG device. Working hardware has been built and is in a late beta stage. Software is still only alpha.
Many people are interested in what is called neurofeedback or EEG biofeedback training, a generic mental training method which makes the trainee consciously aware of the general activity in the brain. This method shows great potential for improving many mental capabilities and exploring consciousness. Other people want to do experiments with brain-computer interfaces or just want to have a look at their brain at work.