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SimThyr

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SimThyr is a simulation program for thyroid homeostasis. It is based on a published nonlinear parametric isomorphic model of thyrotropic feedback control. Applications of SimThyr cover generation of hypotheses for biomedical research, education and presentation. Binaries and sourcecode are available for Mac OS, Mac OS X, Windows, Linux and other Unix derivatives.

SPINA Thyr

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SPINA (structure parameter inference approach) is a method for calculating constant structure parameters of endocrine feedback control systems in vivo from hormone levels obtained from serum or plasma.

A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).

CyberUnits

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CyberUnits is a cross-platform class library for rapid programming of high-performance computer simulations in life sciences. It supports modelling for biomedical cybernetics and systems biology with Object Pascal, S and Matlab.

PUMA repository

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The PUMA Repository (Pascal units for medical applications) is a collection of reusable source code for bioinformatics. It is compatible with Lazarus and Free Pascal, parts of the source code can also be used with Delphi and winsoft Pocket Studio.
Components of the PUMA repository include a unit converter for transforming instrumentation readouts consisting of a numerical value and a measurement unit, and an HL7 engine for reading, parsing, compiling and writing HL7 messages.