CollaboRhythm is a technology platform that enables a new paradigm of healthcare delivery; one where patients are empowered to become active participants and where doctors and other health professionals are transformed into real-time coaches. We believe that this radical shift in thinking is necessary to dramatically reduce healthcare costs, increase quality, and improve health outcomes.
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SPINA (structure parameter inference approach) is a method for calculating constant structure parameters of endocrine feedback control systems in vivo from hormone levels obtained from serum or plasma.
A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).