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InVesalius is a free medical software used to reconstruct structures of the human body. Based on two-dimensional images, acquired using Computed tomography or Magnetic resonance imaging equipments, the software generates virtual three-dimensional models correspondent to anatomical parts of the human body. After reconstructing three-dimensionally DICOM images, the software allows the generation of STL (stereolithography) files. These files can be used for Rapid Prototyping.

The 'epibasix' R Package

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This package contains elementary tools for analysis of common epidemiological problems, ranging from sample size estimation, through 2x2 contingency table analysis and basic measures of agreement (kappa, sensitivity/specificity).

Appropriate print and summary statements are also written to facilitate interpretation wherever possible.

This package is a work in progress, so any comments or suggestions would be appreciated. Source code is commented throughout to facilitate modification. The target audience includes graduate students in various epi/biostatistics courses.


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STIR is Open Source software for use in tomographic imaging. Its aim is to provide a Multi-Platform Object-Oriented framework for all data manipulations in tomographic imaging. Currently, the emphasis is on (iterative) image reconstruction in PET, but other application areas and imaging modalities can and might be added.

STIR is the successor of the PARAPET software library which was the result of a (European Union funded) collaboration between 6 different partners (see Credits).

Conquest DICOM software

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Full featured DICOM server based on and heavily extending the public domain UCDMC DICOM code developed by Mark Oskin.

Insight Segmentation and Registration Toolkit (ITK)

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ITK is an open-source software toolkit for performing registration and segmentation. Segmentation is the process of identifying and classifying data found in a digitally sampled representation. Typically the sampled representation is an image acquired from such medical instrumentation as CT or MRI scanners. Registration is the task of aligning or developing correspondences between data. For example, in the medical environment, a CT scan may be aligned with a MRI scan in order to combine the information contained in both.

The 'epicalc' R Package

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Functions making R easy for epidemiological calculation.

Datasets from Dbase (.dbf), Stata (.dta), SPSS(.sav), EpiInfo(.rec) and Comma separated value (.csv) formats as well as R data frames can be processed to do make several epidemiological calculations.


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JULIDE is a software toolkit developed to perform the 3D reconstruction, intensity normalization, volume standardization by 3D image registration and voxel-wise statistical analysis of autoradiographs of mouse brain sections.


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ClearCanvas Workstation is our friendly, integrated RIS Client and DICOM PACS viewer. Because it is built on top of our highly extensible application framework, we expect that it will be appropriate not just for radiologists and clinicians, but also researchers who want to build new, cutting edge tools that can be easily "tried out" in a clinical environment. Like our other creations, ClearCanvas Worksation is free and open source.

Feature Highlights

  • Very easy to use, intuitive interface
  • Integration with ClearCanvas RIS

The 'epiR' R Package

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A package for analysing epidemiological data. Contains functions for directly and indirectly adjusting measures of disease frequency, quantifying measures of association on the basis of single or multiple strata of count data presented in a contingency table, and computing confidence intervals around incidence risk and incidence rate estimates. Miscellaneous functions for use in meta-analysis, diagnostic test interpretation, and sample size calculations.


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FieldTrip is a Matlab software toolbox for MEG and EEG analysis that is being developed at the Centre for Cognitive Neuroimaging of the Donders Institute for Brain, Cognition and Behaviour together with collaborating institutes. The development of FieldTrip is currently by funding from the BrainGain and the Human Connectome projects.