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BioSig is an open source software library for biomedical signal processing, featuring for example the analysis of biosignals such as the electroencephalogram (EEG), electrocorticogram (ECoG), electrocardiogram (ECG), electrooculogram (EOG), electromyogram (EMG), respiration, and so on. Major application areas are: Neuroinformatics, brain-computer interfaces, neurophysiology, psychology, cardiovascular systems and sleep research. The aim of the BioSig project is to foster research in biomedical signal processing by providing open source software tools for many different applications.


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A Python function library to extract EEG feature from EEG time series in standard Python and numpy data structure. Features include classical spectral analysis, entropies, fractal dimensions, DFA, inter-channel synchrony and order, etc.


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dicompyler is an extensible, fully open source radiation therapy research platform based on the DICOM standard. It also functions as a cross-platform viewer for DICOM and DICOM RT objects. dicompyler is written in Python and is built on pydicom, wxPython, PIL, and matplotlib and runs on Windows, Mac OS X and Linux.


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The goal of OpenIGTLink is to provide a standardized mechanism to connect software/hardware through the network for image-guided therapy (IGT) applications. The features of OpenIGTLink include:


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GIMIAS is a workflow-oriented environment for solving advanced biomedical image computing and individualized simulation problems, which is extensible through the development of problem-specific plug-ins. In addition, GIMIAS provides an open source framework for efficient development of research and clinical software prototypes integrating contributions from the Physiome community while allowing business-friendly technology transfer and commercial product development.

GIMIAS suites are collections of prototypes that build a complete platform for one or more clinical applications.


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MassChroQ (Mass Chromatogram Quantification) software performs quantification of data obtained from mass-spectrometry techniques. It is particularly well suited for peptide quantification of LC-MS (Liquid Chromatography - Mass Spectrometry) data. It performs chromatographic alignment, XIC extraction, peak detection and quantification on identified peptides, with or without isotopic labeling, on high or low resolution data and it takes into account peptide or protein fractionation.


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Apache clinical Text Analysis and Knowledge Extraction System (cTAKES) is an open-source natural language processing system for information extraction from electronic medical record clinical free-text. It processes clinical notes, identifying types of clinical named entities from various dictionaries including the Unified Medical Language System (UMLS) - medications, diseases/disorders, signs/symptoms, anatomical sites and procedures.

MRIdb: Medical imaging database

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MRIdb is an end-to-end data management system for MRI, combining the DCM4CHEE DICOM server with a bespoke front-end packaged into an easily deployable virtual machine. It interfaces directly with MRI scanners and handles image storage, retrieval and export. It provides role-based access control, patient-study assignment, and extensive auditing. MRIdb is the result of an ongoing collaboration between the BSS and the Imaging Sciences Department of Imperial College.


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SCIRun is a problem solving environment or "computational workbench" in which a user selects software modules that can be connected in a visual programing environment to create a high level workflow for experimentation. Each module exposes all the available parameters necessary for scientists to adjust the outcome of their simulation or visualization. The networks in SCIRun are flexible enough to enable duplication of networks and creation of new modules.